About Arthritis
The
word arthritis actually means joint inflammation, and
that is how it is used by clinicians and biomedical
researchers. In the public health world however, arthritis is
used as a shorthand term for arthritis and other rheumatic
conditions—a label for the more than 100 rheumatic diseases and
conditions that affect joints, the tissues which surround
joints and other connective tissue.
Symptoms
The
pattern and location of symptoms can vary depending on the
types of arthritis. Generally, people with arthritis
feel
pain and stiffness in
and around one or more joints. The onset of arthritis symptoms
can develop gradually or suddenly. Arthritis is most often a
chronic disease, so symptoms may come
and go, or persist over time.
Causes
Elevated
uric acid levels cause gout, and specific infections can cause
arthritis of a joint. The causes of many of the other forms of
arthritis are unknown. Scientists are studying the role of
factors such as genetics, lifestyle, and environment on the
various types of arthritis.
Treatment
The focus
of treatment for arthritis is to control pain, minimize joint
damage, and to improve or maintain function and quality of
life. According to the American College of Rheumatology,
the treatment of arthritis might involve the
following:
- Medication.
- Nonpharmacologic therapies
- Physical or occupational
therapy.
- Splints or joint assistive aids.
- Patient education and support.
- Weight loss.
- Surgery.
In
conjunction with medical treatment, self-management of
arthritis pain and symptoms is very important as
well.
Natural
Remedies for Arthritis
People
with rheumatoid arthritis have been reported to have an
impaired antioxidant system, making them more susceptible to
free radical damage. Vitamin E is an important antioxidant,
protecting many tissues, including joints, against oxidative
damage. Low vitamin E levels in the joint fluid of people with
rheumatoid arthritis have been reported.
In a
double-blind trial, approximately 1,800 IU per day of vitamin E
was found to reduce pain from rheumatoid arthritis. Two other
double-blind trials (using similar high levels of vitamin E)
reported that vitamin E had approximately the same
effectiveness in reducing symptoms of rheumatoid arthritis
as anti-inflammatory drugs. In other
double-blind trials, 600 IU of vitamin E taken twice daily was
significantly more effective than placebo in reducing
rheumatoid arthritis, although laboratory measures of
inflammation remained unchanged.
References for
Arthritis Article
- Ozturk HS, Cimen MY, Cimen OB, et al.
Oxidant/antioxidant status of plasma samples from patients
with rheumatoid arthritis. Rheumatol Int 1999;19:35–7.
- Fairburn K, Grootveld M, Ward RJ, et al.
Alpha-tocopherol, lipids and lipoproteins in knee-joint
synovial fluid and serum from patients with inflammatory
joint disease. Clin
Sci 1992;83:657–64.
- Scherak O, Kolarz G. Vitamin E and
rheumatoid arthritis. Arthrit Rheum 1991;34:1205–6
[letter].
- Wittenborg A, Petersen G, Lorkowski G,
Brabant T. Effectiveness of vitamin E in comparison with
diclofenac sodium in treatment of patients with chronic
polyarthritis. Z
Rheumatol 1998;57:215–21 [in
German].
- Kolarz G, Scherak O, El Shohoumi M,
Blankenhorn G. High dose vitamin E for chronic
arthritis. Akt
Rheumatol 1990;15:233–7 [in
German].
- Edmonds SE, Winyard PG, Guo R, et al.
Putative analgesic activity of repeated oral doses of
vitamin E in the treatment of rheumatoid arthritis. Results
of a prospective placebo controlled double-blind
trial. Ann Rheum
Dis 1997;56:649–55.
- Miehle W. Vitamin E in active arthroses
and chronic polyarthritis. What is the value of
alpha-tocopherol in therapy? Fortschr Med 1997;115:39–42.
- National Institutes of
Health
Health
Related Websites
The National Cancer
Institute
The National Eye
Institute
The National Heart, Lung,
and Blood Institute
National Institute on
Aging
National Institute of
Allergy and Infectious Diseases
National Institute of
Arthritis and Musculoskeletal and Skin Diseases
National Institute of
Diabetes and Digestive and Kidney Diseases
National Institute on Drug
Abuse
National Institute of Mental
Health
National Institute of
Neurological Disorders and Stroke
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