About
Carpal Tunnel Syndrome
Carpal
tunnel syndrome is a painful progressive condition caused by
compression of a key nerve in the wrist. It occurs when the
median nerve, which runs from the forearm into the hand,
becomes pressed or squeezed at the wrist.
Symptoms
usually start gradually, with pain, weakness, or numbness in
the hand and wrist, radiating up the arm.
As
symptoms worsen, people might feel tingling during the day, and
decreased grip strength may make it difficult to form a fist,
grasp small objects, or perform other manual tasks. In some
cases no direct cause of the syndrome can be
identified.
Most
likely the disorder is due to a congenital predisposition - the
carpal tunnel is simply smaller in some people than in others.
However, the risk of developing carpal tunnel syndrome is
especially common in those performing assembly line
work.
Treatment
Initial
treatment generally involves resting the affected hand and
wrist for at least 2 weeks, avoiding activities that may worsen
symptoms, and immobilizing the wrist in a splint to avoid
further damage from twisting or bending.
Nonsteroidal anti-inflammatory drugs, such as aspirin,
ibuprofen, and other nonprescription pain relievers, may ease
pain.
Cool (ice)
packs and prednisone (taken by mouth) or lidocaine (injected
directly into the wrist) can relieve swelling and pressure on
the median nerve and provide immediate, temporary
relief.
Stretching
and strengthening exercises can be helpful in people whose
symptoms have abated. If symptoms last for 6 months or more,
doctors may recommend surgery to sever the band of tissue
around the wrist and reduce pressure on the median
nerve.
Prognosis
Recurrence
of carpal tunnel syndrome following treatment is rare. The
majority of patients recover completely. To prevent
workplace-related carpal tunnel syndrome, workers can do
on-the-job conditioning, perform stretching exercises, take
frequent rest breaks, wear splints to keep wrists straight, and
use correct posture and wrist position. Wearing fingerless
gloves can help keep hands warm and flexible.
Research
Several studies
report that people with Carpal Tunnel Syndrome are helped
when given 100 mg of vitamin B6 three times per
day.
Although some
researchers have found benefits with lesser amounts,
using less than 100 mg taken three times per day for
several months has often failed.
Most
doctors assume that people with Carpal Tunnel Syndrome who
respond to vitamin B6 supplementation do so because of an
underlying deficiency.
However,
at least one group of researchers has found vitamin B6 to
"dramatically" reduce pain in people with Carpal Tunnel
Syndrome who did not appear to be
B6-deficient.
Reference for
Carpal Tunnel Article
- Ellis JM,
Azuma J, Watanbe T, Folkers K. Survey and new data on
treatment with pyridoxine of patients having a clinical
syndrome including the carpal tunnel and other defects. Res
Comm Chem Path Pharm
1977;17(1):165–77.
- Ellis JM. Vitamin B6 deficiency in
patients with a clinical syndrome including the carpal
tunnel defect. Biochemical and clinical response to therapy
with pyridoxine. Res Comm Chem Path Pharm
1976;13(4):743–57.
- D’Souza M. Carpal tunnel syndrome:
clinical or neurophysiological diagnosis. Lancet
1985;i:1104–5.
- Driskell JA, Wesley RL, Hess IE.
Effectiveness of pyridoxine hydrochloride treatment on
carpal tunnel syndrome patients. Nutr Rep Internat
1986;34(4):1031–9.
- Ellis JM. Treatment of carpal tunnel
syndrome with vitamin B6. Southern Med J
1987;80(7):882–4.
- Browning DM. Carpal tunnel syndrome:
clinical or neurophysiological diagnosis? Lancet
1985;i:1104–5 [letter].
- Smith GP, Rudge PJ, Peters TJ. Biochemical
studies of pyridoxal and pyridoxal phosphate status and
therapeutic trial of pyridoxine in patients with carpal
tunnel syndrome. Ann Neurol
1984;15:104–7.
- Amadio PC. Pyridoxine as an adjunct in the
treatment of carpal tunnel syndrome. J Hand Surg
1985;10A(2):237–41.
- Stransky M, Rubin A, Lava NS, Lazaro RP.
Treatment of carpal tunnel syndrome with vitamin B6: a
double-blind study. Southern Med J
1989;82(7):841–2.
- Bernstein AL, Dinesen JS. Brief
communication: effect of pharmacologic doses of vitamin B6
on carpal tunnel syndrome, electronencephalographic
results, and pain. J Am Coll Nutri
1993;12:73–6.
- National Institutes of
Health
Health
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