About Herpes
Genital
herpes is a sexually transmitted
disease (STD) caused by the
herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2). Most
genital herpes is caused by HSV-2. Most individuals have no or
only minimal signs or symptoms from HSV-1 or HSV-2 infection.
When signs do occur, they typically appear as one or more
blisters on or around the genitals or rectum.
Symptoms
Most
people infected with HSV-2 are not aware of their infection.
However, if signs and symptoms occur during the first outbreak,
they can be quite pronounced. The first
outbreak
usually occurs within two weeks after
the virus is
transmitted, and the sores typically heal within two to
four weeks. Other signs and symptoms during the primary
episode may include a second crop of sores, and flu-like
symptoms, including fever and swollen
glands.
Causes
HSV-1 and
HSV-2 can be found in and released from the sores that the
viruses cause, but they also are released between outbreaks
from skin that does not appear to be broken or to have a sore.
Generally, a person can only get HSV-2 infection during sexual
contact with someone who has a genital HSV-2 infection.
Transmission can occur from an infected partner who does not
have a visible sore and may not know that he or she is
infected.
HSV-1 can
cause genital herpes, but it more commonly causes infections of
the mouth and lips, so-called "fever blisters." HSV-1 infection
of the genitals can be caused by oral-genital or
genital-genital contact with a person who has HSV-1
infection.
Treatment
There is
no treatment that can cure herpes, but antiviral medications
can shorten and prevent outbreaks during the period of time the
person takes the medication. In addition, daily suppressive
therapy for symptomatic herpes can reduce transmission to
partners.
Natural
Remedies
Most
research on lysine has been done on people with cold sores or
on groups that include both cold sores and genital herpes
sufferers. However, some evidence exists that supplemental
lysine may be effective in the prevention and treatment of
genital herpes. In one preliminary survey, 81% of people with
HSV infections (including genital herpes) reported lysine was
effective for reducing recurrences and shortening healing time
in amounts averaging about 1,000 mg per day.
A small
double-blind trial of people with oral and genital herpes
examined the effects of 1,248 mg or 624 mg of lysine daily
versus placebo. The study found that 1,248 mg per day of
lysine, but not the lower dose, was effective in reducing the
recurrence rate of herpes outbreaks by 57% to 65%, while
neither dose helped reduce the healing time.
References for
Herpes Article
- Walsh DE, Griffith RS, Behforooz A.
Subjective response to lysine in the therapy of herpes
simplex. J
Antimicrob Chemother 1983;12:489–96.
- McCune MA, Perry HO, Muller SA, O’Fallon
WM. Treatment of recurrent herpes simplex infections with
L-lysine monohydrochloride. Cutis 1984;34:366–73.
- Griffith RS, Walsh DE, Myrmel KH, et al.
Success of L-lysine therapy in frequently recurrent herpes
simplex infection. Dermatologica 1987;175:183–90.
- Simon CA, Van Melle GD, Ramelet AA.
Failure of lysine in frequently recurrent herpes simplex
infection. Arch
Dermatol 1985;121:1678
[letter].
- Arens M, Travis S. Zinc salts inactivate
clinical isolates of herpes simplex virus in-vitro.
J Clin
Microbiol 2000;38:1758–62.
- Wahba A. Topical application of zinc
solutions: A new treatment for herpes simplex infections of
the skin? Acta Derm
Venereol 1980;60:175–7.
- Finnerty EF. Topical zinc in the treatment
of herpes simplex. Cutis 1986;37:130–1.
- Brody I. Topical treatment of recurrent
herpes simplex and post-herpetic erythema multiforme with
low concentrations of zinc sulphate solution.
Br J
Derm 1981;104:191–4.
- Eby GA, Halcomb WW. Use of topical zinc to
prevent recurrent herpes simplex infection: review of
literature and suggested protocols.
Med
Hypotheses 1985;17:157–65.
- National Institutes of
Health
Health
Related Websites
The National Cancer
Institute
The National Eye
Institute
The National Heart, Lung,
and Blood Institute
National Institute on
Aging
National Institute of
Allergy and Infectious Diseases
National Institute of
Arthritis and Musculoskeletal and Skin Diseases
National Institute of
Diabetes and Digestive and Kidney Diseases
National Institute on Drug
Abuse
National Institute of Mental
Health
National Institute of
Neurological Disorders and Stroke
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