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About Herpes

Genital herpes is a sexually transmitted disease (STD) caused by the herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2). Most genital herpes is caused by HSV-2. Most individuals have no or only minimal signs or symptoms from HSV-1 or HSV-2 infection. When signs do occur, they typically appear as one or more blisters on or around the genitals or rectum.

Symptoms

Most people infected with HSV-2 are not aware of their infection. However, if signs and symptoms occur during the first outbreak, they can be quite pronounced. The first outbreak  usually occurs within two weeks after the virus is transmitted, and the sores typically heal within two to four weeks. Other signs and symptoms during the primary episode may include a second crop of sores, and flu-like symptoms, including fever and swollen glands.

Causes

HSV-1 and HSV-2 can be found in and released from the sores that the viruses cause, but they also are released between outbreaks from skin that does not appear to be broken or to have a sore. Generally, a person can only get HSV-2 infection during sexual contact with someone who has a genital HSV-2 infection. Transmission can occur from an infected partner who does not have a visible sore and may not know that he or she is infected.

HSV-1 can cause genital herpes, but it more commonly causes infections of the mouth and lips, so-called "fever blisters." HSV-1 infection of the genitals can be caused by oral-genital or genital-genital contact with a person who has HSV-1 infection.

Treatment

There is no treatment that can cure herpes, but antiviral medications can shorten and prevent outbreaks during the period of time the person takes the medication. In addition, daily suppressive therapy for symptomatic herpes can reduce transmission to partners.

Natural Remedies

Most research on lysine has been done on people with cold sores or on groups that include both cold sores and genital herpes sufferers. However, some evidence exists that supplemental lysine may be effective in the prevention and treatment of genital herpes. In one preliminary survey, 81% of people with HSV infections (including genital herpes) reported lysine was effective for reducing recurrences and shortening healing time in amounts averaging about 1,000 mg per day.

A small double-blind trial of people with oral and genital herpes examined the effects of 1,248 mg or 624 mg of lysine daily versus placebo. The study found that 1,248 mg per day of lysine, but not the lower dose, was effective in reducing the recurrence rate of herpes outbreaks by 57% to 65%, while neither dose helped reduce the healing time.

References for Herpes Article

  • Walsh DE, Griffith RS, Behforooz A. Subjective response to lysine in the therapy of herpes simplex. J Antimicrob Chemother 1983;12:489–96.  
  • McCune MA, Perry HO, Muller SA, O’Fallon WM. Treatment of recurrent herpes simplex infections with L-lysine monohydrochloride. Cutis 1984;34:366–73.  
  • Griffith RS, Walsh DE, Myrmel KH, et al. Success of L-lysine therapy in frequently recurrent herpes simplex infection. Dermatologica 1987;175:183–90.  
  • Simon CA, Van Melle GD, Ramelet AA. Failure of lysine in frequently recurrent herpes simplex infection. Arch Dermatol 1985;121:1678 [letter]. 
  • Arens M, Travis S. Zinc salts inactivate clinical isolates of herpes simplex virus in-vitro. J Clin Microbiol 2000;38:1758–62.  
  • Wahba A. Topical application of zinc solutions: A new treatment for herpes simplex infections of the skin? Acta Derm Venereol 1980;60:175–7.  
  • Finnerty EF. Topical zinc in the treatment of herpes simplex. Cutis 1986;37:130–1.  
  • Brody I. Topical treatment of recurrent herpes simplex and post-herpetic erythema multiforme with low concentrations of zinc sulphate solution. Br J Derm 1981;104:191–4.  
  • Eby GA, Halcomb WW. Use of topical zinc to prevent recurrent herpes simplex infection: review of literature and suggested protocols. Med Hypotheses 1985;17:157–65.  
  • National Institutes of Health 

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